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Top 9
June 2025
Best Cat Flea And Tick Treatment
We made a list of the top 9 Cat Flea And Tick Treatment based on verified reviews, popularity and other factors which we summarized for you in this list.
Best Choice
1
Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 1-Month Supply
Advantage
9.0
VIEW DEAL
Buy on Amazon
✓
Advantage II Large Cat is a leading brand in cat flea treatment and prevention for large cats over 9 lbs., at least 8 weeks of age
✓
Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
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Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
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Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
✓
Fragrance-free formula, waterproof after 24 hours of application
Learn more
on Amazon
More Info
2
Seresto Cat Vet-Recommended Flea & Tick Treatment & Prevention Collar for Cats | 8 Months Protection
Seresto
8.9
VIEW DEAL
Buy on Amazon
✓
Vet-recommended, premium flea & tick protection for cats & kittens without the price tag
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Long-lasting flea and tick collar kills & repels fleas for 8 continuous months
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Seresto is the #1 veterinarian recommended flea & tick collar*
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Starts working within 24 hours to kill & repel fleas and ticks by contact so pests don’t have to bite your cat to die
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Hassle-free, non-greasy, easy-to-use flea & tick protection
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on Amazon
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3
Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 1-Month Supply
Advantage
8.8
VIEW DEAL
Buy on Amazon
✓
Advantage II Small Cat is a leading brand in cat flea treatment and prevention for small cats 5-9 lbs., at least 8 weeks of age
✓
Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
✓
Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
✓
Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
✓
Fragrance-free formula, waterproof after 24 hours of application
Learn more
on Amazon
More Info
11% Discount
4
PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs
PetArmor
8.4
VIEW DEAL
Buy on Amazon
✓
EFFECTIVE, WATERPROOF FLEA TREATMENT FOR CATS: PetArmor Plus is a waterproof, flea & tick topical prevention for cats that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
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TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Cats. PetArmor Plus for Cats has a powerful formula that starts to kill fleas within 24 hours.
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BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Cat Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
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FLEA AND TICK PROTECTION: PetArmor Plus for Cats flea drops protects your furry family members from brown dog ticks, American dog ticks, Lone Star ticks, and deer ticks (which may transmit Lyme disease).
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EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with six (6) waterproof topical applications that provide your pet flea protection and control for (6) months
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on Amazon
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32% Discount
5
PetArmor for Cats, Flea & Tick Treatment for Cats (Over 1.5 Pounds), Includes 3 Month Supply of Topical Flea Treatments
PetArmor
8.2
VIEW DEAL
Buy on Amazon
✓
CAT FLEA AND TICK CONTROL: SENTRY Fiproguard topical flea and tick prevention for cats kills fleas, ticks and chewing lice for up to 30 days.
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VET QUALITY FORMULA: SENTRY Fiproguard is a vet-quality formula flea treatment that contains the active ingredient fipronil.
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FOR KITTENS AND CATS: PetArmor topical flea treatment for cats and kittens 8 weeks and older for up to 30 days after application and helps prevents infestations of adult fleas.
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FLEA AND TICK PREVENTION: PetArmor for cats helps you protect your furry family member from the diseases fleas and ticks carry, including deer ticks that may transmit Lyme disease.
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INCLUDES: Three (3) 0.017 fl. oz. waterproof topical applications for cat flea and tick control. For best results, apply flea and tick treatment for cats directly to dry skin on your cats back, between the shoulder blades, on a monthly basis.
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on Amazon
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18% Discount
6
Amazon Basics Topical Flea Treatment for Large Cats (Over 9 Pounds), 4 Count (Previously Solimo)
Amazon Basics
8.0
VIEW DEAL
Buy on Amazon
✓
FAST-ACTING FLEA MEDICATION FOR CATS: Eliminates fleas in just 12 hours, providing your large cat with swift relief from discomfort with our effective flea medication for cats
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LONG-LASTING FLEA PREVENTION FOR CATS: Protect your cat from infestations for up to 4 weeks with each application of this flea remover, providing continuous and reliable flea prevention for cats
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TOPICAL CAT FLEA DROPS FOR REINFESTATION: This cat flea medicine proactively kills reinfesting fleas within 2 hours, efficiently halting the flea lifecycle
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SUITABLE CAT FLEA MEDS FOR LARGE CATS: Specifically formulated for cats weighing over 9 pounds, offering targeted flea control with our dedicated cat flea meds for your furry companion
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SUITABLE CAT FLEA MEDS FOR LARGE CATS: Specifically formulated for cats weighing over 9 pounds, offering targeted flea control with our dedicated cat flea meds for your furry companion
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on Amazon
More Info
7
TevraPet FirstAct Plus Flea and Tick Topical for Cats over 1.5lbs, 3 Dose Waterproof Flea and Tick Control/Prevention for 3 Months
TevraPet
7.9
VIEW DEAL
Buy on Amazon
✓
Proven formula - Contains fipronil and (S)-Methoprene, the same active ingredients as Frontline Plus for cats
✓
Effective - This flea and tick topical kills fleas, flea eggs and larvae, chewing lice, and all stages of ticks including those that may transmit Lyme disease
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Waterproof - use on your cat monthly, no need to reapply after swimming or bathing
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3 month supply - includes 3 applicators for 3 months of flea and tick Prevention; Apply these flea drops Once every 30 days
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Trusted quality - made in Germany in a certified eu-gmp facility, tested to meet rigorous standards of quality and consistency
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Continuous protection - your cat is protected Tip to tail for up 30 days after application
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Age range description: all life stages
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on Amazon
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17% Discount
8
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments
Hartz
7.8
VIEW DEAL
Buy on Amazon
✓
Topical drop formula kills fleas and deer ticks
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Includes 3 monthly treatments in easy to apply, single dose tubes
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Repels mosquitoes for 18 days
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For use on cats and kittens 12 weeks and older weighing 5 pounds and over
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on Amazon
More Info
11% Discount
9
Amazon Basics Flea and Tick Topical Treatment for Cats (Over 1.5 Pounds), 3 Count (Previously Solimo)
Amazon Basics
7.6
VIEW DEAL
Buy on Amazon
✓
Same product, new look―This product is identical in manufacturing and formulation as the Solimo brand
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Amazon Basics Flea & Tick starts eliminating fleas and ticks within 24 hours of treatment
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Active ingredients prevent flea infestations by killing flea eggs, flea larvae, mosquitos, biting flies and chewing lice
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One application provides up to 30 days of protection
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Waterproof: 24 hours after application your pet's treatment is protected against rain and water activities
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Packaging received may vary: you may receive product in Solimo or Amazon Basics packaging
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Amazon Basics Flea and Tick Topical does not expire
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on Amazon
More Info
How we create our
“
Top 10
“ lists?
Our algorithms collect and evaluate information on millions of products and rank them based on customer reviews, popularity, price and more.
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